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Karen J. Hendershott, MD, FACS, to Practice at Arizona Oncology’s Oro Valley Location
By Christina Caldwell - Thursday Dec 29, 2022
Arizona Oncology is thrilled to announce Karen J. Hendershott, MD, FACS, is now practicing breast surgical oncology at the new Oro Valley location in addition to her practices at the Silverbell and Green Valley locations. As a premier provider of cancer care, Arizona Oncology is excited to bring Dr. Hendershott’s compassionate surgical expertise to the community in Northwest Tucson.

Dr. Hendershott is a board-certified surgeon and a Fellow of the American College of Surgeons. She joined the Tucson surgical team at Arizona Oncology in 2020 and has 15 years of experience specializing in the care of breast cancer patients. She completed her fellowship training in breast surgical oncology at Maimonides Medical Center, and a research fellowship at Memorial Sloan Kettering, where she was also named Chief Academic Fellow. Dr. Hendershott has multiple publications in peer-reviewed journals and has presented at national surgical conferences.

“As a breast cancer survivor myself, I recognize that treatments can be challenging, and having access to high-quality care is essential,” said Dr. Hendershott. “Having a breast surgical oncology location in Oro Valley allows our team to bring comprehensive care and support to our patients right here in their community, close to home.”

Arizona Oncology is proud to provide care from breast surgical oncologists like Dr. Hendershott who are recognized leaders in their field. The team’s in-depth knowledge of breast cancer biology, genetics, and the most advanced surgical options helps patients achieve the best possible outcomes. Dr. Hendershott specializes in the surgical management of genetic, familial, and triple-negative breast cancers and has a special interest in invasive lobular cancers. She has additional training in the performance of oncoplastic techniques to maximize cosmetic outcomes in breast conservation surgery. In addition to nipple-sparing mastectomies, she offers “aesthetically flat” mastectomy scars using complex closures. Dr. Hendershott also performs Goldilocks procedures on women desiring breast mounds without formal reconstruction.

“We focus on the individual’s needs and goals because no two breast cancer patients are alike,” said Dr. Hendershott. “Our team is with the patient every step of the way, developing a personalized plan with leading-edge technology and a holistic healing strategy.”

The Oro Valley office is located at 1850 E. Innovation Park Dr., Oro Valley, AZ, 85755. To learn more or to schedule an appointment, call 520-879-6749 or visit

About Arizona Oncology
Arizona Oncology is one of the largest medical groups in Arizona, with more than 50 physicians devoted exclusively to providing comprehensive, compassionate, and high-quality cancer care. Since its inception in 1998, Arizona Oncology has led with the philosophy that it’s beneficial to provide cancer therapies in a community setting, close to patients' homes and support systems. Arizona Oncology specializes in Medical, Gynecologic, and Radiation Oncology, Hematology, Breast Surgery, Colorectal Surgery, Urology, Research, Genetic Risk Assessment, and patient ancillary programs. The physicians and their staff treat patients in many communities throughout the state including Glendale, Goodyear, Green Valley, Phoenix, Prescott, Prescott Valley, Scottsdale, Oro Valley and Tucson. For more information, visit

Arizona Oncology is an affiliate of The US Oncology Network (The Network). This collaboration unites AO with more than 1,400 independent physicians dedicated to delivering value-based, integrated care for patients — close to home. Through The Network, these independent doctors come together to form a community of shared expertise and resources dedicated to advancing local cancer care and to delivering better patient outcomes. The US Oncology Network is supported by McKesson Specialty Health, whose coordinated resources and infrastructure allow doctors in The Network to focus on the health of their patients, while McKesson focuses on the health of their practices. AO also participates in clinical trials through US Oncology Research, which has played a role in more than 100 FDA-approved cancer therapies.